Amyloidosis Presenting as Severe Bleeding Diathesis

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Amyloidosis presenting as severe bleeding diathesis

Bleeding is one of the rare presentations of Amyloidosis. The mechanism behind spontaneous or periinterventional bleeding in patients of amyloidosis is complex and involves multiple co-existing factors like coagulation factor deficiency, abnormal synthesis of coagulation factors due to advanced liver dysfunction, acquired Von Willebrand disease, platelet dysfunction, amyloid angiopathy and othe...

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Celiac Crisis Presenting with Refractory Hypokalemia and Bleeding Diathesis.

Celiac disease is an immune mediated disorder elicited by the ingestion of gluten in genetically susceptible person and associated with some HLA subtypes. It is characterized by chronic inflammation of small intestine associated with villous atrophy. Symptoms usually appear when weaning from breast milk is done and gluten is introduced in diet. Failures to thrive, chronic diarrhea, vomiting abd...

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Perioperative evaluation of bleeding diathesis.

The differential diagnosis of a long APTT with a normal prothrombin time can be due to either a clotting factor deficiency or the presence of an inhibitor, which can be distinguished by using a plasma-mixing study. The various clotting factor deficiency states are reviewed. Clinical bleeding following cardiac bypass surgery due to acquired factor V and thrombin antibodies is also reviewed.

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Bleeding Diathesis in Hemodialysis Patients

End-stage renal disease patients, particularly those treated with hemodialysis (HD), suffer from complex hemostatic disorders. Patients with uremia may experience two opposite he‐ mostatic complications: bleeding diathesis and thrombotic tendencies. Bleeding diathesis in uremic patients is primarily seen due to abnormalities in primary hemostasis, particularly platelet function disorder and imp...

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ژورنال

عنوان ژورنال: International Journal of Medical and Dental Sciences

سال: 2017

ISSN: 2320-1118,2454-8952

DOI: 10.19056/ijmdsjssmes/2017/v6i2/149915